None of the material in this collection dates from the years when the Holden Drug Company was operated by the Holdens. Apart from a scattering of turn-of-the-century advertising pamphlets, all items found here are prescription records dating from 1910 or later. As such, they form an interesting record of population shifts in the older part of Stockton. The records from 1941, for instance, bear mostly Japanese surnames, while records from 1963 show a preponderance of Spanish names.

In 1900 there were twelve drug stores in Stockton. In 1920 there were twenty-two. Of that number, three (Central, Eagle, and Holden Drug) had been in operation in 1900. The same three continued in business in 1940 when there were thirty-seven druggists in Stockton, four of whom bore Japanese surnames.

Collection is open for research.