Register of the William J. Rutter Papers

Processed by Julia Bazar and Robin Chandler; machine-readable finding aid created by James Lake
UCSF Library & CKM
Archives and Special Collections
530 Parnassus Ave.
San Francisco, CA 94143-0840
Phone: (415) 476-8112
Fax: (415) 476-4653
Email: http://www.library.ucsf.edu/collections/archives/contact
URL: http://www.library.ucsf.edu/collections/archives
© 1998
The Regents of the University of California. All rights reserved.

Note

History --History, California --General Biological and Medical Sciences --Biological Sciences --Biochemistry Biological and Medical Sciences --Biotechnology

Register of the William J. Rutter Papers

Collection number: MSS 94-54

UCSF Library & CKM



Archives and Special Collections

University of California, San Francisco

Contact Information:

  • UCSF Library & CKM
  • Archives and Special Collections
  • 530 Parnassus Ave.
  • San Francisco, CA 94143-0840
  • Phone: (415) 476-8112
  • Fax: (415) 476-4653
  • Email: http://www.library.ucsf.edu/collections/archives/contact
  • URL: http://www.library.ucsf.edu/collections/archives
Processed by:
Julia Bazar and Robin Chandler
Date Completed:
August 1995
Encoded by:
James Lake
© 1998 The Regents of the University of California. All rights reserved.

Descriptive Summary

Title: William J. Rutter Papers
Collection number: MSS 94-54
Extent: 13 cartons
Repository: University of California, San Francisco. Library. Archives and Special Collections.
San Francisco, California 94143-0840
Shelf location: For current information on the location of these materials, please consult the Library's online catalog.
Language: English.

Administrative Information

Access

Collection is open for research, except for Subgroup 5, which is restricted.

Preferred Citation

[Identification of item], William J. Rutter Papers, MSS 94-54, Archives & Special Collections, UCSF Library & CKM

Biographical Statement

[This biographical statement is based primarily on information in extensive interviews with Dr. Rutter conducted in 1992-1993. Editing in progress; transcripts to be deposited in the Molecular Biology and Biotechnology Archives, Special Collections, UCSF Library.]
Born on August 28, 1928, William J. Rutter received a B.A. in Biochemistry from Harvard University in 1949, after a year at Brigham Young University and a stint in the Navy. He went on to get an M.S. in (?) from the University of Utah (1950) and a Ph.D. in (?) from the University of Illinois (1952).
After post-doctoral work at the University of Wisconsin (1952-1954) and the Nobel Institute in Sweden (1954-1955), Rutter joined the faculty at the University of Illinois (1955-1963). In 1962-1963, he went to Stanford on a Guggenheim Fellowship, and then returned to Illinois as a full professor for two years (1963-1965). He held a joint professorship in genetics and biochemistry at the University of Washington from 1965-1968, before becoming Hertzstein Professor of Biochemistry and Chairman of the Department of Biochemistry and Biophysics at UCSF in 1969.
Chairman of the department until 1982, Rutter became the Director of the Hormone Research Institute at UCSF in 1983. In addition he held numerous extramural appointments, including serving on advisory committees for various national and international laboratories and scientific organizations. He also held offices in various professional societies and served on a number of journal editorial boards. Rutter became an emeritus professor in 1991.
Among Rutter's diverse research contributions are, discovery and characterization of the three RNA polymerase transcription systems operating in eucaryotic gene expression, cloning and structural and functional analysis of the insulin gene, nucleotide sequencing of hepatitis B virus, and development (with Chiron corporation and Merck) of the first commercial genetically engineered human vaccine, for hepatitis B.
Though an innovative researcher, Rutter is best known at UCSF for his leadership as chairman and his encouragement of a collaborative, interdisciplinary approach to research. He transformed a mediocre department into a vital and groundbreaking research facility that has become a foundation for the biotech industry centered in the San Francisco Bay Area. Another of his contributions is the promotion of biotechnology and the fostering of cooperative research efforts between industry and academia. In 1981, he and two colleagues formed Chiron Corporation, where he remains as chairman of the board of directors.

Education and Early Career

Rutter became interested in parasitic diseases in high school after listening to his grandfather's descriptions of the tropical diseases he had observed as a British Military officer in India. He graduated from Harvard intending do go on to medical school, but after auditing medical school classes at the University of Utah, he decided to concentrate on the research sciences. He received a master's degree from Utah in 1950 and then a Ph.D. in 1952 at the University of Illinois. At the University of Illinois, Rutter completed a dissertation on galactosemia, a metabolic disease.
Rutter began his post-doctoral studies in enzyme chemistry with Henry Lardy at the Institute for Enzyme Research at the University of Wisconsin, Madison (1952-54). An interest in enzyme mechanism took him to Sweden for another year of post-doctoral work with future Nobel Prize winner, Hugo Theorell at the Nobel Institute (1954-55).
Returning to the University of Illinois, Urbana 1955 to take a tenure track position in the chemistry department(1955-65), Rutter continued his research on enzyme mechanism, concentrating on aldolase. During the mid-1950's, he became interested in biological problems and initiated studies of the regulation of RNA transcription. Fostering this interest, Rutter went to Stanford in 1962 on a Guggenheim Fellowship and worked with Clifford Grobstein, head of Biology, on embryonic development of the pancreas.
Returning to Illinois in 1965 with his new biological focus, Rutter found his position in the chemistry department less attractive. In 1965, he accepted a professorship in the Departments of Biochemistry and Genetics at the University of Washington (1965-69). He chose Washington because of its strong genetics department and modest teaching load which allowed him to concentrate on research. While continuing his work on defining the molecular basis of the pancreatic system, he also began to focus on the mechanisms of DNA transcription, using the simple eukaryotic systems (yeast) that the department, under Herschel Roman, had developed.

University of California at San Francisco

In 1965 UCSF began attempts to recruit Rutter as chairman of the biochemistry department. Worried that administrative duties would restrict his research, he hesitated for four years. At the time, medical schools were not considered ideal settings to pursue research in molecular biology. However, in the mid 1960's, Holly Smith, head of Medicine, J. Englebert Dunphy, head of Surgery, and others decided to improve basic science at UCSF, and saw Rutter as one who could lead this endeavor. Rutter was also attracted by a large number of open positions in the department which would allow him to shape its direction.
Rutter finally accepted the chairmanship in 1969, committed to creating a eukaryotic biology program based on cooperative multidisciplinary research. He had the department renamed the Department of Biochemistry and Biophysics and began to recruit promising researchers interested in a molecular approach using the latest technology. Gordon Tomkins, recruited from the NIH in 1970 to be vice-chairman, was in partnership with Rutter, a vital force in restructuring the department until his untimely death in 1977.
Rutter and his large laboratory group conducted a diverse research program initially centered on gene structure and expression. Among the highlights are the cloning of the rat insulin gene in 1977, conducted against the backdrop of the recombinant DNA controversy and a fierce race with other laboratories. In 1977, Rutter and Herbert Boyer (of UCSF), co-inventor with Stanley Cohen of recombinant DNA technology, were asked to testify before the U.S. Senate regarding alleged misuse of a plasmid used in the cloning process.
He and his group later studied the structure of genes for other peptide hormones, including several growth factors, glucagon, and somatostatin. In the early 1980's, his laboratory turned to the problem of the regulation of gene expression in specific differentiated cells. Genetic engineering techniques were also applied to the analysis of hepatitis B virus. Collaborating with a group at the University of Washington, Rutter and coworkers at UCSF and Chiron cloned the gene for the outer viral coat, the component of the virus that induces an immune response. Largely because of the promise the hepatitis work had for the development of a vaccine, Rutter and two colleagues founded Chiron Corp., in Emeryville, CA, in 1981.

Hormone Research Institute

Suggestions of conflict of interest due to of his ties with the biotechnology industry prompted Rutter to step down as chairman in 1982. In 1983 he became director of the Hormone Research Institute (HRI), one of UCSF's independent research units. Succeeding Choh Hao Li, as director, he reoriented research to a molecular approach based on advanced technology. He relinquished the directorship 1989, but remained a member of the institute and head of a lab group. He retired from the university in 1994.

Biotech (Hana, Chiron, etc.)

Rutter played an active role in the development of the Biotech Industry. His most successful business venture was the establishment of Chiron, founded by Rutter and his former Stanford colleague, Ed Penhoet, in 1981. Chiron became one of the major biotechnology firms in the San Francisco Bay Region: In 1991 Chiron merged with Cetus, another local biotech firm. Rutter's success with Chiron placed him on a list of "Molecular Millionaires" issued by Genetic Engineering News in 1987, which reported him as holding Chiron stock worth over 20 million dollars. Rutter has been Chairman of the Board since the company's founding.
In addition to his Chiron activities, Rutter attempted in 1981 to help establish the Harbor Bay Isle bio-tech business park in Alameda, CA. Rutter's first Bio-tech venture, with his partners Michael Urdea and C.K. Chang, was the short lived company called Biopolymer. Rutter also served on the boards of Meridian Instruments (1982-1988) and HANA Biologics (1980 to 1983), which absorbed Biopolymer in 1981. Since 1995 he has served on the Board of Directors of Ciby-Geigy and the Board of Trustees of the Carnegie Institution of Washington. He acted as a consultant to Abbott Laboratories (1960-1975), Eli Lilly Co. (1977-1980) and Merck and Co. (1977-1981).

Other

Rutter also served as Treasurer of the American Society of Biological Chemists (1970-1976), as President of the Pacific Slope Biochemical Conference (1975-76), and as President of the American Society for Developmental Biology (1975-1976). Elected to the National Academy of Sciences in 1984, and the American Academy of Arts and Sciences in 1987, Rutter also served on Advisory committees for National Laboratories (Los Alamos, Oak Ridge, the Naval Biosciences Center, and Scripps), International Laboratories (Hagedorn Research Laboratory of the Nordisk Labrotorium, Zentrum fur Molekulare Biologie, and International Centre for Genetic Engineering and Biotechnology) and Foundations (Cystic Fibrosis, March of Dimes, Keystone Life Science Study Center, and California Council on Science and Technology). Service on Boards or Committees also links him to the National Institute of Health and the National Science Foundation.
As of 1995 Rutter had well over 300 publications to his name.

Scope and Content

The Rutter Collection consists of 12 cartons and 1 manuscript box containing files primarily documenting his association with the University of California at San Francisco (1969-1994) as professor of biochemistry, department chair and lab director including associated professional commitments: membership in professional organizations, work on advisory boards, and consulting. Some material on his involvement in the Biotech industry is included, although there is little or no evidence of Chiron activities. Chiron was co-founded by Rutter and Edward Penhoet in 1981. The papers include administrative and professional correspondence, subject files, some financial and personnel documents, minutes and agendas, conference materials and other materials that he produced during his career at UCSF.
The collection does not include any documentation of actual research, i.e., lab notebooks or experimental data, though administrative files on MUAs, grants, and patents are a part of the collection. Photocopies of some experimental data are included in the Patent files, but the actual lab notebooks apparently no longer exist. There are also extensive correspondence files covering the exchange of scientific information and materials.
The papers in this collection were all created or collected by Rutter in the course of his career, but they come from various offices; having moved with him from the Department of Biochemistry and Biophysics to the Hormone Research Institute. Sally Hughes, a historian with the History of Health Sciences Department at UCSF arranged for the donation of the material as a part of her oral history research project with Rutter. The majority of the records came to Special Collections from the Hormone Research Institute office by way of Dr. Hughes. Additional records were transferred directly from the Hormone Research Lab.
The collection is organized into five subgroups. Each subgroup is arranged by series as necessary. The first covers Rutter's activities as Hertzstein Professor of Biochemistry (1969-1991), including his administrative duties as head of the Department of Biochemistry and Biophysics (1969-1981) and as director of the Hormone Research Institute (1982-1989). Rutter's filling system maintained no distinction between his activities.
The second subgroup documents Rutter's wider involvement with the UC system and UCSF (particularly membership on the School of Medicine Executive Committee and other committee work).
The third includes materials on his various Professional Commitments: membership in professional organizations, service on editorial boards and as a manuscript and grant reviewer, consultant work and service on a variety of advisory boards.
The fourth subgroup documents his Business Commitments.
Patent materials form the fifth subgroup. These materials are preserved for their historic value, but are temporarily restricted for sensitive legal reasons.
Folders are usually arranged alphabetically within their series or subseries, exceptions include Travel which is arranged chronologically, and a part of Correspondence which is arranged hierarchically.

Related Collections

Title: Department of Biochemistry and Biophysics: Annual Reports (1970- )


This collection contains photocopies of the Annual reports of the Department of Biochemistry and Biophysics beginning with Rutter's chairmanship. Of special interest would be the Chairman's Report and the research activities of individual lab groups.
Title: Rutter Oral History


Currently being edited, when completed a copy will be available as part of the Molecular Biology and Biotechnology Collection in the Archives.

Subgroup/Series Descriptions

 

SUBGROUP 1: Hertzstein Professor, Chair Department of Biochemistry and Biophysics, and Director of the Hormone Research Institute, 1964-1992, n.d.

Scope and Content Note

This subgroup contains materials covering the entire period of Rutter's connection to UCSF. It includes documents pertaining to William J. Rutter's roles as Hertzstein Professor of Biochemistry and chair of the Department of Biochemistry and Biophysics and later as director of the Hormone Research Institute, an independent research unit at UCSF.
 

Series I. Correspondence, 1964-1992, n.d.

Additional Note

Correspondence files range from his negotiations with the Administration prior to his arrival in 1969 as Chairman of the Department of Biochemistry and Biophysics (1969-1981), and Hertzstein Professor of Biochemistry (1969-1991), through his directorship of the Hormone Research Institute (1982-1989) and beyond.
This series includes memo's, departmental communications, correspondence with colleagues, letters to and from legislators, Christmas cards and more. Some reprints can also be found in these files.
Most of the correspondence (1970-1990) is arranged alphabetically. Some folders concern specific subjects, including memos between HRI and the Biochemistry Department and Rutter's Correspondence with the University negotiating his acceptance of the Chairmanship of the department.
Limited correspondence is also found in other series such as Series IV (Research), subseries D which includes letters between Rutter and Colleagues concerning exchanges of material.
 

Series II. Administration, 1973-1992, n.d.

Additional Note

This series consists of subject files relating to the administration of both the Biochemistry/Biophysics department and the Hormone Research Institute, which is classified as an Independent Research Unit within UCSF.
Subjects include issues of Lab safety, patent administration, financial matters and media coverage. Rutter's testimony to the U.S. Senate on the use of an unapproved plasmid during his insulin research is found in this section. Also included are files covering the creation of the Biomolecular Research Center (an on campus facility to provide advanced technologies in Biochemical and Molecular Biology to UCSF investigators) and the controversial lease and cooperation arrangements between the department, the University and the Howard Hughes Medical Center. In addition, there is a file documenting Rutter's receipt of the 1982 Faculty Research Lecturer Award. Series is arranged alphabetically
 

Series III. Research, 1972-1991, n.d.

Scope and Content Note

This collection does not contain any direct scientific experimentation data or lab notebooks. There are no files following a project from inception to completion, but some documentation of the various steps of research and the administration of research, as well as the dissemination information.
 

Subseries A. Research Projects, 1972-1988, n.d.

Scope and Content Note

The Research Projects subseries includes: correspondence, clippings, press releases drafts of articles and copies of reports on various projects. There are files concerning Rutter's research on Insulin, into the Hepatitis B vaccine and on Somatostatin. This subseries also includes files documenting interest in commercial dissemination of vectors and other materials.
 

Subseries B. Memorandum of Understanding, 1972-1980.

Scope and Content Note

MUAs (Memoranda of Understanding and Agreement), documents describing proposed grant supported experiments and the levels of biocontainment and other safety measures necessary, are submitted to the university Biosafety Commission for approval. They are then sent to the NIH for registration or approval. Disapproval by NIH of all or part of the MUA leads to the issuance of rewriting of NIH Grant award notifications. These files include some Grant award notifications.
 

Subseries C. Grant Applications & Information, 1976-1990, n.d.

Scope and Content Note

Grant applications and awards are necessary to fund research. This subseries includes grant applications and other information concerning the status of grants applied for by Rutter to fund his basic researches. Included are requests for funding research in Insulin, Karposi's Sarcoma (AIDS), Parasitic diseases, Hepatitis B Vaccine, among others.
 

Subseries D. Collaboration and Cooperation (Exchange of Material), 1973-1993, n.d.

Additional Note

One of the largest of the research subseries, subseries D consists of Rutter's files documenting his communication and collaboration with other scientists. These files include letters requesting Permission to use figures from Rutter's research, Rutter's requests of materials from others, and correspondence on collaborations. The majority of the documents are correspondence requesting materials (plasmids, vectors, etc.) from Rutter by other researchers. Most of these requests are filed alphabetically by the material requested. Some requests were separated out by type of research or researcher's name. Each of these are organized in separate alphabetical sequences within the subseries.
 

SUBGROUP 2: University of California, San Francisco and University of California: Committees, Advisory Boards, etc., 1969-1994.

Scope and Content Note

During his career at UCSF, Rutter was involved in committees and concerns that extended past the confines of the department of biochemistry and biophysics. He served on various committees, on-campus and within the larger UC system, as well as expressing concern about campus safety issues, testifying to the State Legislature about proposed biotechnology regulation, and dealing with additional governmental organizations. Documents in this series include agendas, minutes and correspondence, as well as flyers and other materials.
 

Series I. School of Medicine Executive Committee, 1969-1986.

Scope and Content Note

Rutter was a member of the School of Medicine Executive Committee from 1969-1976. He retained files of minutes (incomplete), agendas, informational memos and other correspondence for every year except 1973. The collection also contains Executive Committee information from 1985-86. Topics covered include the creation of a Department of Genetics, increasing the size to the medical school class, and relationships between academia and business [see also series II].
 

Series II. Other Committees, 1973-1991.

Scope and Content Note

Rutter's other on-campus commitments, include an active involvement in discussions on the use and distribution of facilities [see "Facilities"] and on the relationship of academia to industry [see "Relationship to Industry"]. He was also involved in UC system-wide, serving on the Board for the UCLA Symposium and as a consultant to the UC Davis Molecular Biology program.
 

Series III. Other UC/UCSF Related Commitments/Concerns, 1969-1988, n.d.

Scope and Content Note

This series covers activities besides committee membership which had direct connections with his position at UCSF. These include testimony at the California State Legislature Recombinant DNA Hearing, and liaison work with ABAG (Association of Bay Area Governments) and the Fair Political Practices Commission. He also participated in the 1969 Vietnam Moratorium program on campus.
 

SUBGROUP 3: Professional Commitments, 1974-1994.

Scope and Content Note

This subgroup covers Rutter's various professional commitments including membership in a number of professional organizations; his service on editorial boards and as a manuscript and grant reviewer; and his service as a consultant and on advisory boards both domestic and international. These files include routine correspondence, personalized correspondence and other information. Some files include newsletters or other publications.
 

Series I. Professional Organizations, 1974-1993.

Scope and Content Note

Rutter was a member of a number of professional organizations. He was elected to the National Academy of Sciences in 1984 (files include information from the Committee on Human Rights and the Election of Foreign members). He was elected to the American Academy of Arts and Sciences in 1987 and became a fellow of the American Association for the Advancement of Science in 1992. He also belonged to several International scientific bodies, including the International Union of Biochemistry. As a member of the IUB's Biotech Group he was sent "ballots" on various funding proposals. He also served on the board of the California Council on Science and Technology.
 

Series II. Consulting and Advisory Boards, 1980-1993, n.d.

Scope and Content Note

Rutter served on numerous consulting and advisory boards, both national and international. Files contain correspondence and other materials (some minutes and agendas) relating to Rutter's participation in visiting committees, conference planning and boards of directors or scientific advising for Universities, Non-profits, and other research institutes or foundations. These include, among others: the California Foundation for Molecular Biology, a Columbia University Visiting Committee, the Cystic Fibrosis Foundation, the Oak Ridge National Laboratory, the Wiezman Institute (Israel) and the Zentrum fur Molekulare Biologie Heidelberg (Germany).
 

Series III. Manuscript Reviews, 1982-1991.

Scope and Content Note

He also served on manuscript review or editorial boards for several publications, including the Proceedings of the National Academy of Science (PNAS) and Diabetes. Some files (particularly PNAS), include manuscripts and reviews, some contain reviews without manuscripts and some contain only correspondence about the reviews or the reviewing process.
 

Series IV. Grant Reviews, 1975-1990.

Scope and Content Note

This series contains two folders of miscellaneous grant reviews and one folder of reviews for the U.S.-Israel Bi-National Foundation.
 

Series V. Travel: Conferences, Seminars, Meetings and Retreats, 1973-1992.

Scope and Content Note

Rutter attended numerous conferences, seminars, meetings and retreats world wide. There are scattered files from trips between 1973 and 1984. Extensive files exist for the year's 1985-1991. Materials in these files range from conference brochures, correspondence about speaking arrangements and other background material to expense reports and receipts. Some folders also include the texts of talks given by Rutter, abstracts or proceedings from the conference, or reprints of individual articles.
 

SUBGROUP 4: Business Commitments, 1979-1987.

Scope and Content Note

This subgroup includes folders on Hana Biologics, the Harbor Bay Isle biotech park and Meridian Instruments.
There are no files covering Rutter's co-founding of Chiron corporation or service on the Board of directors, though other files do make mention of business related endeavors, such as the "Outside Professional Activities Reports" in Subgroup 1, Series II (Administration).
 

SUBGROUP 5: Patents, 1973-1993. [RESTRICTED]

Scope and Content Note

This series contains files covering Rutter's applications for patents for various inventions or processes. Included are files on Patent Interferences and lawsuits involving Eli Lilly and Genentech. These files are temporarily restricted.

Container List

 

SUBGROUP 1 -- DEPARTMENT OF BIOPHYSICS AND BIOCHEMISTRY & HORMONE RESEARCH INSTITUTE, UNIVERSITY OF CALIFORNIA AT SAN FRANCISCO.

Carton Carton 1

Series I -- Correspondence

Carton Ctn. 1, Folder 1

"A" 1973-1989, n.d.

Folder 2

"B" 1975-1989, n.d.

Folder 3

"C" 1974-1988, n.d.

Physical Description: [Tape]
Folder 4

"D" 1975-1988

Folder 5

"E" 1976-1983

Physical Description: [PHOTOS]
Folder 6

"F" 1971-1990

Folder 7

"G" 1970-1989, n.d.

Physical Description: [FAX]
Folder 8

"H" 1973--1989, n.d.

Folder 9

"I" 1973-1984

Folder 10

"J" 1971-1989

Folder 11

"K" 1979-1991, n.d.

Folder 12

"L" 1972-1988, n.d.

Folder 13

"M" 1979-1988, n.d.

Physical Description: [Tape]
Folder 14

"N" 1971-1987, n.d.

Physical Description: [PHOTOS, Newsprint]
Folder 15

"O" 1979-1894, n.d.

Folder 16

"P" 1973-1990, n.d.

Folder 17

"R" 1975-1988

Folder 18

"S" 1972-1988, n.d.

Folder 19

"T" 1977-1989, n.d.

Physical Description: [PHOTO]
Folder 20

"U" 1987, n.d.

Folder 21

"W" 1973-1986, n.d.

Folder 22

"General Correspondence -- 1990." 1990

Folder 23

"Biochemistry/Biophysics Department" 1983-1992, n.d.

Folder 24

"Archive Biochemistry Department" 1989-1990, n.d.

Folder 25

"Biochemistry Department to HRI" 1984-1990

Folder 26

"Archive Other Departments" 1989-1990

Folder 27

"Chancellor to WJR" 1988-1989

Folder 28

"WJR on Chairmanship" 1964-1969, 1972

Folder 29

"Rao, D. R. --Mysore India --CFTRI" 1986, n.d.

Folder 30

"High School Student's Information Request" 1977

Folder 31

"Christmas Cards" 1985-1987, n.d.

Folder 32

"Christmas Cards" 1986, n.d.

Carton Carton 2

Series II -- Administration

Carton Ctn. 2, Folder 1

"Animal Research Approval" 1981-1991, n.d.

Folder 2

"Animal Research Approval" 1981-1991, n.d.

Folder 3

"Bayer" 1984, n.d.

Folder 4

"Biomolecular Research Center -- BRC" 1985, n.d.

Folder 5

"Biomolecular Research Center -- BRC" [PERSONNEL INFO] 1986-1988

Folder 6

"Bionet" 1984-1985, n.d.

Folder 7

"Faculty Research Lecturer Award" 1982

Folder 8

"Financial Matters" 1979-1981, n.d.

Folder 9

"Financial Memos, Materials" 1980-1981

Folder 10

"Hormone Research Center Donors" 1983, n.d.

Folder 11

"Howard Hughes Medical Institute--Lease, corresp" 1977, 1979-1980

Physical Description: [N]
Folder 12

"Human Research Approval" 1983-1985

Folder 13

"Laboratory Business, misc." 1983-1988

Folder 14

"Laboratory Certification -- Biosafety Commission" 1987-1989, n.d.

Folder 15

"News Service" 1976-1979

Physical Description: [N]
Folder 16

"News Service" 1980-1981

Folder 17

"NIH Guidelines for Research Involving DNA Molecules" 1986

Folder 18

"Outside Professional Activities Reports" 1981-1988

Folder 19

"Patents: Administration" 1973-1981, n.d.

Folder 20

"Patents: Administration (Supreme Court Rulings)" 1980, n.d.

Folder 21

"Radiation Safety" 1982-1988, n.d.

Folder 22

"Radiation Safety" 1986-1992, n.d.

Folder 23

"Research Reports" 1973-1985, n.d.

Folder 24

"Senate Sub-Committee Hearing, Washington, DC (pBR322)" 1977-1978

Folder 25

"University Statement of Economic Interest" 1982, n.d.

 

Series III-- Research

Carton Cartons 2-3

Sub-series A -- Research Projects

Carton Ctn. 2, Folder 26

"Hepatitis" 1972-1981

Physical Description: [N]
Folder 27

"Insulin: MUA, corresp., press" 1977-1979

Physical Description: [N]
Folder 28

"Insulin Expression" [CONFIDENTIAL - in French] 1978, n.d.

Physical Description: [N]
Folder 29

"Insulin Correspondence" 1976-1977

Physical Description: [N]
Folder 30

"Insulin Press Release and Photos" 1977, n.d.

Physical Description: [photos & negatives]
Folder 31

"Insulin (Press)" 1977-1978

Physical Description: [N]
Folder 32

"Insulin (Plasmid 3 -- pBR322)" 1977

Folder 33

"Insulin Like Growth Factor paper (Morgan/Jarnigan/Roth)" n.d.

Folder 34

"Saccharomyces papers (L.J. DeGennaro)" 1977, n.d.

Folder 35

"Somatostatin" 1979-1981

Carton Ctn. 3, Folder 1

"Amersham -- Commercial Distribution of Vectors" [CONFID] 1985-1987

Folder 2

"Amersham -- Commercial Distribution of Vectors" [CONFID] 1986-1988

Physical Description: [FAX]
Folder 3

"Genzyme --Commercial Distribution of PDI" 1985

Folder 4

"Merck --MUA's, misc." 1978-1981, n.d.

Folder 5

"Merck --Correspondence" 1977-1978

Folder 6

"Merck --Correspondence" 1977-1980

Folder 7

"Merck --Correspondence" 1977-1983

Folder 8

"Merck --Correspondence" 1981-1987

Physical Description: [N] [TELEGRAM]
Folder 9

"Repligen" 1986

Carton Carton 3

Sub-Series B -- MUAs (Memorandum of Understanding and Agreement)

Carton Ctn. 3, Folder 10

"Correspondence" 1977-1980, n.d.

Folder 11

"AM-21344 (Pancreas)" 1979-1980

Folder 12

"GM-21830 (Yeast)" 1978-1980

Folder 13

"Eli Lilly" 1978-1979

Folder 14

"Merck" 1979-1980

Folder 15

"Miscellaneous" 1978-1980

Folder 16

"Miscellaneous" 1979-1980

Folder 17

"Superseded MUAs" 1972-1978

Carton Carton 3

Sub-Series C -- Grant Applications & Info.

Carton Ctn. 3, Folder 18

"BRC Joint Proposal to NIH (Insulin)" 1987, n.d.

Folder 19

"Karposi's Sarcoma Grant Application" 1983-1984

Folder 20

"Karposi's Sarcoma Grant Application" 1983-1985

Folder 21

"Kroc Foundation (Insulin)" 1982-1984

Folder 22

"MacArthur Foundation Program--Biology of Parasitic Diseases" 1984

Folder 23

"Multiple User Request to Academic Senate (w/A.L. Burlingame)" 1983

Folder 24

"National Science Foundation - Electron Microscope 1980-1981

Folder 25

"National Science Foundation (rejected)" 1990

Folder 26

"NIH-NIDDDK (Differention in the Pancreas)" 1990-1992

Folder 27

"SCRC-- UC Grant Application (Hepatitis B Vaccine) 1982

Folder 28

"U.S. - Israeli Bi-National Foundation" 1990-1991

Physical Description: [FAX]
 

Sub-Series D -- Collaboration and Cooperation (Exchange of Materials)

Carton Carton 3

sub-sub Series 1 -- Collaborators (by name)

Carton Ctn. 3, Folder 29

"Bachovchin, William" 1986

Folder 30

"Barker, Peter -- Insulin Receptor" 1986-1988

Physical Description: [Photos]
Folder 31

"Bartlett, Paul -- Carboxy" 1989-1991

Physical Description: [FAX]
Folder 32

"Berhanu, Paulos" 1986-1991

Folder 33

"Carpentier, Jean-Louis" 1989-1991

Physical Description: [FAX]
Folder 34

"Damsky, Caroline" 1985, n.d.

Folder 35

"Davis, J. -- Duke University, NC. 1986

Folder 36

"Fahenestock, Margaret -- NGF" 1989

Physical Description: [FAX]
Folder 37

"Fisher, Edward --Lysophospholipase" 1989

Folder 38

"Goldsmith, Betsy" 1990-1991

Physical Description: [FAX]
Folder 39

"Grumbach, Melvin" 1986

Folder 40

"Hodes, M.E." 1980-1986

Physical Description: [Photos]
Folder 41

"Huber, Klaus 1988

Folder 42

"Jarett, Leonard" 1987

Folder 43

"Jones, John Bryan" 1985-1986

Folder 44

"Kahn, Ronald" 1986

Folder 45

"Kaiser, E.T." 1982-1988

Folder 46

"Lane, Daniel" 1985

Folder 47

"Muller, Werner --IR, IGFI, IGFII-R" 1989

Folder 48

"Naor, David" 1991

Physical Description: [FAX]
Folder 49

"Pawson, Tony" 1986

Folder 50

"Reddy, Jan" 1983-1986

Physical Description: [Photo]
Folder 51

"Reddy, Jan -- Mounted Photos" n.d.

Physical Description: [Photos]
Folder 52

"Rochefort, Henri" 1990

Folder 53

"Sheffield, James -- IGF's 1990

Folder 54

"Shows, Thomas" 1980-1983

Folder 55

"Siddle, Kenneth -- Insulin Receptor" 1985-1987

Folder 56

"Wang, L.H." 1986-1990

Physical Description: [Photos]
Carton Carton 4

sub-sub Series 2 -- Collaborations (by type and Miscellaneous)

Carton Ctn. 4, Folder 1

"American Type Culture Collection Deposits" 1981-1982

Folder 2

"American Type Culture Collection" 1985-1986, n.d.

Folder 3

"Clinical Experiments" 1982

Folder 4

"Insulin Receptor Collaborations" 1985-1991

Folder 5

"IGF [Insulin-Like Growth Factor] II Collaborators" 1987-1990

Physical Description: FAX
Folder 6

"Miscellaneous Collaborations" 1977-1993

Physical Description: FAX [Photos on Paper]
Folder 7

"Miscellaneous Collaborations" 1981-1986, n.d.

Folder 8

"Permission to Use Figures" 1973-1992

Folder 9

"Papers with Rutter Acknowledgments" 1986-1988

Carton Cartons 4-5

sub-sub Series 3 -- Exchange of Materials

Carton Ctn. 4, Folder 10

"Requests from Rutter to Others" 1980-1986, n.d.

Folder 11

"Requests from Rutter to Others" 1984-1993, n.d.

Folder 12

"Alkaline Phosphatase" 1985-1992

Folder 13

"Amylase" 1982-1994

Folder 14

"Beta-Gal RSV" 1986-1989

Folder 15

"Beta-Gal RSV" 1986-1994

Physical Description: FAX
Folder 16

"Carboxypeptidase" 1984-1993

Physical Description: FAX
Folder 17

"Cells" 1987-1992

Physical Description: FAX
Folder 18

"Chymotrypsin" 1990-1994

Folder 19

"C-jun cDNA" 1989, 1995

Folder 20

"EGF" 1984-1993

Physical Description: PHOTO
Folder 21

"Elastase, Lipase, Chymotrypsin" 1981-1994

Folder 22

"Hepatitis" 1980-1991, n.d.

Folder 23

"Human Placental Library" 1984-1990

Folder 24

"Insulin" 1978-1987

Folder 25

"Insulin" 1986-1990

Physical Description: FAX
Folder 26

"Insulin" 1990-1994

Physical Description: FAX
Folder 27

"Insulin Receptor" 1985-1986

Folder 28

"Insulin Receptor" 1985-1988

Physical Description: PHOTOS
Folder 29

"Insulin Receptor" 1988-1994

Physical Description: FAX
Folder 30

"Insulin-Like Growth Factor (IGFI & IGFII) 1987-1990

Folder 31

"Insulin-Like Growth Factor I - Receptor (IGFI-R) 1988

Folder 32

"Insulin-Like Growth Factor I -Receptor 1988-1995

Physical Description: PHOTOS, FAX
Folder 33

"Insulin-Like Growth Factor II - Receptor (IGFII-R) 1987-1989

Physical Description: FAX
Folder 34

"Insulin-Like Growth Factor II - Receptor 1989-1995

Physical Description: FAX
Folder 35

"Libraries (other than placental)" 1986-1989

Carton Ctn. 5, Folder 1

"MRL3" 1990-1993

Physical Description: FAX
Folder 2

"Nerve Growth Factor" 1983-1986

Folder 3

"Nerve Growth Factor" 1986-1989

Folder 4

"Nerve Growth Factor" 1990-1995

Physical Description: FAX
Folder 5

"PANS" 1990-1994

Physical Description: FAX
Folder 6

"PDI" 1986-1990

Physical Description: FAX
Folder 7

"PDI" 1990-1994

Physical Description: FAX
Folder 8

"Probe -- Flag-enterokinase-HMK" 1992

Physical Description: FAX
Folder 9

"Somatostatin" 1981-1986

Folder 10

"Somatostatin" 1986-1989

Folder 11

"Somatostatin" 1989-1994

Folder 12

"Trypsin" 1987-1990

Folder 13

"Vectors" 1980-1986

Folder 14

"Vectors" 1983-1992

Folder 15

"Vector -- Lambda gt22" 1987-1990

Folder 16

"Vector -- Lambda gt22" 1987-1991

Physical Description: FAX
Folder 17

"Vector -- pECE" 1986-1990

Physical Description: FAX
Folder 18

"Vector -- pECE" 1987-1992

Physical Description: FAX
Folder 19

"Vector--Pur1" 1993

 

SUBGROUP 2 -- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO AND UNIVERSITY OF CALIFORNIA: COMMITTEES, ADVISORY BOARDS, ETC.

Carton Carton 5

Series I -- Executive Committee

Carton Ctn. 5, Folder 20

"School of Medicine Executive Committee" 1969-1970

Folder 21

"School of Medicine Executive Committee" 1970-1971

Folder 22

"School of Medicine Executive Committee" 1971-1972

Folder 23

"School of Medicine Executive Committee" 1974-1975

Folder 24

"School of Medicine Executive Committee" 1975-1976

Folder 25

"School of Medicine Executive Committee" 1976-1977

Folder 26

"School of Medicine Executive Committee" 1985-1986

Carton Carton 6

Series II -- Other Committees

Carton Ctn. 6, Folder 1

"Academic Senate" 1990-1991, n.d.

Folder 2

"Board of Overseers Meeting" 1980

Folder 3

"Council of Chairmen" 1973-1974

Folder 4

"Council of Chairmen -- Chairmen's Retreat" 1975

Folder 5

"Diabetes Steering Committee" 1992

Folder 6

"Epidemiology Review Committee" 1987-1988, n.d.

Folder 7

"Facilities: Ad-hoc Committee to Advise Dean on Space" 1984

Folder 8

"Facilities: Dean's Space Committee - WJR" 1983-1984

Folder 9

"Facilities: Dean's Retreat" 1988

Folder 10

"Facilities: UCSF Long-term Planning Committee" 1990-1992

Folder 11

"Facilities: Campus Facilities" 1991, n.d.

Folder 12

"Facilities: Second Campus Committee" 1992, n.d.

Folder 13

"Institute of Health and Aging -- UCSF" 1984-1994

Folder 14

"Laurel Heights" 1987-1988

Physical Description: [N]
Folder 15

"Liver Core Center" 1983, 1988

Folder 16

"Markey Award" 1985-1987

Folder 17

"PIBS (Programs in Biological Sciences)" 1988

Folder 18

"President's Fellowship Program" 1987-1988

Folder 19

"Relationship to Industry, Advisory Panel" 1981-1983

Folder 20

"Relationship to Industry, Advisory Panel" 1981-1983

Folder 21

"Relationship to Industry" 1987

Folder 22

"Rights to Intellectual Property Committee --UCSF" 1982

Folder 23

"School of Medicine -- Advisory Committee" 1969-1971

Folder 24

"School of Medicine -- Advisory Committee" 1972-1975

Folder 25

"School of Medicine -- Advisory Committee" 1976-1977

Folder 26

"School of Medicine -- Dean's Advisory Committee, etc." 1984-1988

Folder 27

"School of Medicine -- Development Committee" 1992

Folder 28

"Search Committee: Capitol Projects Coordinator" [includes some reference letters] 1985

Folder 29

"Search Committee: Res. Associate, Structural and Mass Spectrometry" 1983

Folder 30

"UC Davis Molecular Biology Consultant" 1986

Folder 32

"UCLA Symposium Board" 1982-1986

Folder 33

"UCLA Symposium Board" 1986-1988

Physical Description: FAX
Folder 34

"UCLA Symposium/Keystone Center Collaboration" 1986-1989, 1992

Folder 35

"UCSF 1984 Symposium on HBV- Organizing Committee" 1981-1984

Folder 36

"University Committees" 1987-1988

Folder 37

"V.A. Hospital Committee" 1981

Carton Carton 6

Series III -- Other UC/UCSF Related Commitments/Concerns

Carton Ctn. 6, Folder 38

"ABAG (Association of Bay Area Governments) Academic Research and Biotech Survey" 1987-1988

Folder 39

"California State Legislature-- Recombinant DNA Hearing" 1981

Folder 40

"Campus Violence" 1980

Folder 41

"Fair Political Practices Commission" 1981-1983

Folder 42

"Gifts to the University" 1981-1982

Folder 43

"Gifts to the University" 1981, n.d.

Folder 44

"Report of the President to the Regents" 1985, 1988

Folder 45

"Vietnam Moratorium (Rutter)" 1969

 

SUBGROUP 3 -- PROFESSIONAL COMMITMENTS

Carton Carton 7

Series I -- Professional Organizations

Carton Ctn. 7, Folder 1

"American Academy of Arts and Sciences" 1987-1991

Folder 2

"American Academy of Arts and Sciences" 1992-1993

Physical Description: [Memorabilia]
Folder 3

"American Academy of Arts and Sciences and American Association for the Advancement of Science" 1993-1994

Folder 4

"American Association for the Advancement of Science -- Ad Hoc Expert Panel on Genetic Engineering" 1981

Folder 5

"American Society for Biological Sciences" 1985-1986

Folder 6

"American Society for Cell Biology" 1974-1975, 1990, n.d.

Folder 7

"American Society for Cell Biology" 1985-1991, n.d.

Folder 8

"American Society for Microbiology" 1986-1991

Physical Description: [Mem. Cards]
Folder 9

"California Council on Science and Technology" 1989

Physical Description: FAX
Folder 10

"California Council on Science and Technology" 1989-1990

Physical Description: FAX
Folder 11

"California Council on Science and Technology" 1988, 1990, n.d.

Physical Description: FAX
Folder 12

"COSTED (Commission on Science and Technology in Developing Countries" 1984-1985

Folder 13

"Endocrine Society and Molecular Endocrinology" 1986-1989

Folder 14

"Endocrine Society" 1988-1991

Folder 15

"International Society of Developmental Biologists" 1982-1984

Folder 16

"International Union of Biochemistry -- Biotech Group" 1985-1988

Folder 17

"International Union of Biochemistry -- Biotech Group" 1988-1991

Physical Description: FAX
Folder 18

"International Union of Pure and Applied Chemistry" 1985

Folder 19

"National Academy of Science--Correspondence" 1984

Folder 20

"National Academy of Science--Correspondence" 1985

Folder 21

"National Academy of Science--Correspondence" 1986

Folder 22

"National Academy of Science--Correspondence" 1987

Folder 23

"National Academy of Science--Correspondence" 1988

Folder 24

"National Academy of Science--Correspondence" 1989

Folder 25

"National Academy of Science--Correspondence" 1990

Folder 26

"National Academy of Science--Correspondence" 1991

Folder 27

"National Academy of Science--Correspondence" 1992

Folder 28

"National Academy of Science -- Letter to Members " 1986-1992

Folder 28

(same ) -- "By-laws" 1988, 1991

Carton Cartons 7-8

Series II -- Consulting and Advisory Boards

Carton Ctn. 7, Folder 29

"California Foundation for Molecular Biology" [inc. Finan. 1988-1990

Folder 30

"California Foundation for Molecular Biology" records, tax 1982-1992

Folder 31

"California Foundation for Molecular Biology" returns, etc.] 1987-1993, n.d.

Carton Ctn. 8, Folder 1

"Columbia University -- Visiting Committee" 1980

Folder 2

"Cystic Fibrosis Foundation" 1982-1985

Folder 3

"Cystic Fibrosis Foundation" 1985-1986

Folder 4

"Cystic Fibrosis Foundation" 1985-1987

Folder 5

"Development Center for Biotechnology -- Taipei" 1990

Folder 6

"Institute for the Advancement of Health" 1983

Folder 7

"International Rice Research Institute" 1985

Folder 8

"Japan -- Human Frontier Science Program" 1987

Folder 9

"Japan -- Misc. Consulting" 1986-1988

Folder 10

"Life Science Research Foundation" 1981-1989

Folder 11

"Life Science Research Foundation" 1983-1994

Folder 12

"Life Science Research Foundation" 1990-1991, n.d.

Folder 13

"Livermore-Los Alamos Project -- Chromosome Specific Human DNA Library" 1983-1985

Folder 14

"March of Dimes Advertisement (and telethon)" 1984

Physical Description: [slides, photos]
Folder 15

"Naval Bioscience Laboratory" 1982, 1984

Folder 16

"Nordisk Laboratory" 1981, n.d.

Folder 17

"Oak Ridge National Laboratory" 1984, n.d.

Folder 18

"Oak Ridge National Laboratory" May 1985

Folder 19

"Oak Ridge National Laboratory" Nov. 1985

Folder 20

"Oak Ridge National Laboratory" 1986

Folder 21

"Oak Ridge National Laboratory" March 1987

Folder 22

"Oak Ridge National Laboratory" Oct. 1987

Folder 23

"Oak Ridge National Laboratory" 1985-1988, n.d.

Folder 24

"OSCC - Pancreatic Cancer Working Group" 1984-1985

Folder 25

"OSCC - Pancreatic Cancer Working Group" 1985-1986

Physical Description: PHOTO
Folder 26

"OSCC - Pancreatic Cancer Working Group" 1986-1987

Folder 27

"OSCC - Pancreatic Cancer Working Group" 1987-1989

Folder 28

"OSCC (Organ Systems Coordinating Center) Newsletter" 1986-1988

Folder 29

"Scleroderma Research Foundation" 1991

Folder 30

"Scripps Institute" 1975-1987

Folder 31

"Weizman Institute -- Israel" 1985-1989

Physical Description: [fax]
Folder 32

"Zentrum fur Molekulare Biologie - Heidelberg" 1982-1984, n.d.

Folder 33

"Zentrum fur Molekulare Biologie - Heidelberg" 1983-1985

Folder 34

"Zentrum fur Molekulare Biologie - Heidelberg" 1984-1987

Carton Carton 9

Series III -- Manuscript Reviews

Carton Ctn. 9, Folder 1

"Archives of Biochemistry and Biophysics" 1984-1985

Folder 2

"Brenner-Lennox Journal (Molecular Biology and Medicine)" 1982-1986

Folder 3

"Diabetes" 1982-1985

Folder 4

"Encyclopedia of Human Biology" 1987

Folder 5

"Journal of Molecular Engineering" 1989

Folder 6

"Proceedings of the National Academy of Sciences (PNAS) -- Miymura" 1980-1990

Physical Description: FAX, PHOTOS
Folder 7

"PNAS -- Aghib" 1992

Folder 8

"PNAS -- Cross, et al" 1993

Physical Description: PHOTOS
Folder 9

"PNAS -- Walker, et al" 1993

Physical Description: PHOTOS on Paper
Folder 10

"PNAS -- Yeh, et al" 1993

Folder 11

"Protein Engineering" 1985-1988

Folder 12

"Manuscript Review--Correspondence 1983-1987

Carton Carton 9

Series IV -- Grant Reviews

Carton Ctn. 9, Folder 13

"U.S. - Israeli Bi-National Foundation" 1976-1977, 1986, 1988, 1990-1991

Folder 14

"Grant Reviews - Miscellaneous" 1975-1990

Folder 15

"Grant Reviews - Miscellaneous" 1980-1985

Carton Cartons 9-10

Series V -- Travel: Conferences, Seminars, Meetings, Retreats

Carton Ctn. 9, Folder 16

"International Symposium on the Control of Transcription -- Calcutta" Feb. 12-15, 1973

Folder 17

"Tehran Symposium -- Tehran, Iran" May 2-6, 1976

Folder 18

"China Trip" (1979-1984?) Oct.-Nov. 1979

Folder 19

"American Diabetes Association -- San Antonio" June 14, 1983

Folder 20

"Wright State University, Ohio" June 16, 1983

Folder 21

"IUB-Genome Lecture Tour -- Costa Rica" Aug. 21-Sept. 3, 1983

Folder 22

"Modern Approaches to Vaccines -- Cold Spring Harbor, NY." Aug. 31-Sept. 4, 1983

Folder 23

"Lawrence Livermore Lab Advisory Meeting-- Livermore, CA." Sept. 12, 1983

Folder 24

"Whitehead Institute Symposium -- MIT -- Cambridge, MA" Oct. 2-4, 1983

Folder 25

"Berzelius Lectureship -- Karolinska Institutet -- Stockholm" Oct. 11, 1983

Folder 26

"Inter-Center Seminar on IARCs & Biotechnology -- Philippines" April 23-27, 1984

Physical Description: PHOTOS
Folder 27

"NIH -- Rockville, Maryland" Oct. 6-9, 1985

Folder 28

"West Central State Biochemistry Conference -- Lawrence, KS" Oct. 24, 1985

Folder 29

"Biotechnology Conference -- Tokyo" Dec. 3-4, 1985

Physical Description: [TRANSPARENCIES]
Folder 30

"Faculty Retreat -- Asilomar, CA" Jan. 3-5, 1986

Folder 31

"Roche-UCLA Symposium -- Viruses and Human Cancer -- Park City, UT" Feb. 2-9, 1986

Folder 32

"Western Winter Workshop -- UCLA Symposium -- Vectors for Gene Transfer in Animals -- Lake Tahoe, CA" Feb. 9-12, 1986

Folder 33

"Lilly-UCLA Symposium -- Proteases in Biological Control and Biotechnology -- Park City, UT" Feb. 9-15, 1986

Folder 34

"Gordon Research Conference -- Kallikreins & Kinins -- Oxnard, CA" Feb. 17-21, 1986

Folder 35

"Li Luye, Chinese (PRC) Ambassador to U.N. at Syntex -- Palo Alto, CA" Feb. 24, 1986

Folder 36

"First Annual ASM Conference on Biotechnology -- Washington, DC" Mar. 20-23, 1986

Folder 37

"UCLA Symposium Board -- Keystone, CO" April 6, 1986

Folder 38

"March of Dimes -- Basic Research Advisory Committee -- Scottsdale, AZ" April 6-9, 1986

Folder 39

"U of Michigan biomedical Research Council Forum -- Ann Arbor" April 26, 1986

Folder 40

"UNIDO -- PSA Meeting of the ICGEB -- NY" May 17-18, 1986

Folder 41

"Tribute to Melvin Grumbach -- UCSF" May 23, 1986

Folder 42

"Kroc Lecture -- Boston" May 28-29, 1986

Folder 43

"Cold Spring Harbor Symposium -- Molecular Biology of Homo Sapiens -- NY" June 1-4, 1986

Folder 44

"FASEB -- ASBC Meeting -- Receptor Kinase Function -- Washington, DC." June 10, 1986

Folder 45

"Genetic Phsico-Chemical Approaches for Analysis of Biological Catalysts -- Florence" June 16-20, 1986

Folder 46

"Society of Chinese Biochemists in America -- San Francisco" June 30 -July 2, 1986

Folder 47

"FASEB Symposium on Somatic Cell Genetics -- Vermont" July 6-11, 1986

Folder 48

"Brown-Hazen Lecture (WJR Presenter) --Albany, NY" Sept. 25-26, 1986

Folder 49

"Basel Liver Meeting -- Basel, Switzerland" Oct. 13-15, 1986

Folder 50

"BIO Fare Tokyo -- Tokyo" Oct. 15-19, 1986

Folder 51

"Weizman Review Board -- Israel" Nov. 4-7, 1986

Folder 52

"Kroc Lecture (WJR) -- U of Texas -- Houston" Dec. 15, 1986

Folder 53

"Upjohn NDDM Conference -- Augusta, MI." Jan. 12-14, 1987

Folder 54

"UCSF Faculty Retreat -- Asilomar, CA" Jan. 15-17, 1987

Folder 55

"NIH Symposium on Animal Virology -- Bethesda, MA" Feb. 2-3, 1987

Folder 56

"Battelle Biotechnology Workshop -- San Francisco" Feb. 17-18, 1987

Carton Ctn. 10, Folder 1

"U. of Calgary --Insulin Action and Diabetes" -- Calgary" Mar. 26-27, 1987

Folder 2

"March of Dimes -- Basic Research Advisory Committee -- Scottsdale, AZ" March 28-April 1, 1987

Folder 3

"Roche-UCLA Symposium --Mechanisms of Control of Gene Expression -- Steamboat Springs, CO" March 28-April 2, 1987

Folder 4

"107th Annual Meeting Pharmaceutical Association -- Kyoto" April 2-4, 1987

Folder 5

"Protein Engineering '87 -- Oxford, UK" April 5-8, 1987

Folder 6

"Indiana Research Expo -- Indiana U. -- Bloomington, IN" Apr. 22-23, 1987

Folder 7

"National Academy of Science -- Annual Meeting -- DC." Apr. 26-29, 1987

Folder 8

"Notre Dame University -- South Bend, IN" Apr. 27-29, 1987

Folder 9

"Gastroenterology Research Group Symposium -- U. of Michigan -- Ann Arbor" May 10, 1987

Folder 10

"ZMBH -- Molecular Biology of Pathogens -- Heidelberg" May 21-23, 1987

Folder 11

"Nobel Conference -- Pathogenesis of Non-Insulin Dependent Diabetes Mellitus -- Stockholm" May 25-27, 1987

Folder 12

"American Society of Biological Chemists -- Annual Meeting -- Philadelphia" June 7-11, 1987

Folder 13

"Capri Lecture in Biotechnology --- Regulation of Mammalian Cell Growth -- Capri, Italy" Sept. 27 -Oct. 2, 1987

Folder 14

"Fritz Lipmann Memorial Symposium -- Berlin" Oct. 4-6, 1987

Folder 15

"Kroc Lecture -- U. of Pennsylvania -- Philadelphia" Dec. 13-14, 1987

Folder 16

"UCSF Faculty Retreat -- Asilomar, CA" Jan. 15-17, 1988

Folder 17

"Nature -- Horizons in Molecular Biology -- Tokyo" Jan. 26-28, 1988

Folder 18

"UCSF/Hong Kong Postgraduate Course -- Hong Kong" Jan. 30-31, 1988

Folder 19

"New England Area Insulin Action Committee -- Boston" Feb. 8, 1988

Folder 20

"2nd World Conference on Diabetes Research -- Juvenile Diabetes Foundation International -- Monaco" March 6-9, 1988

Folder 21

"UCLA Symposium Board Meeting -- Los Angeles " Apr. 27-28, 1988

Folder 22

"Molecular Responses to Virus Infection -- Stanford" May 9, 1988

Folder 23

"International Conference on Immunopharmacology -- Osaka, Japan" May 15-19, 1988

Physical Description: FAX
Folder 24

"Bicentennial Biochemistry Conference -- Adelaide, Australia" May 17-20, 1988

Folder 25

"Dynamics of Protein Development and Function -- Heidelberg" June 26, 1988

Folder 26

"IUB -- International Congress of Biochemistry -- Prague" July 10-15, 1988

Folder 27

"British Society for Cell Biology -- Oxford" Sept. 20-23, 1988

Folder 28

"Cold Spring Harbor -- Pancreatic B Cell -- NY" Oct. 17, 1988

Folder 29

"International Diabetes Federation Conference -- Sydney" Nov. 23, 1988

Folder 30

"Hans Popper Memorial Symposium -- New Concepts in Medicine and Biology -- CUNY -- NY" Dec. 8, 1988

Physical Description: FAX
Folder 31

"American Diabetes Association Research Symposium -- Laurel Heights, UCSF" Dec. 16, 1988

Folder 32

"AAAS Annual Meeting -- San Francisco" Jan. 15-16, 1989

Folder 33

"Swiss Diabetes Foundation Annual Meeting (in Honor of A. E. Renold) -- Geneva" Jan. 20-21, 1989

Physical Description: FAX
Folder 34

"UCSF Postdoctoral Panel" Jan. ?, 1989

Folder 35

"Forum on Cancer Research, U. of Tennessee -- Cell Regulators and Cancer -- Memphis" April 14, 1989

Folder 36

"Jacques Monod Conference -- Receptors -- Paris" June 26-30, 1989

Physical Description: FAX
Folder 37

"Trends in Biotechnology -- Stockholm" Mar. 11-14, 1990

Physical Description: FAX
Folder 38

"International Symposium: Gene Expression and Signal Transduction -- UC-Irvine" Apr. 22-24, 1990

Folder 39

"New Approaches to the Structure-Function Analysis of Proteases -- Castle Szirak, Budapest, Hungary" Aug. 19-24, 1990

Physical Description: FAX
Folder 40

"Advances in Receptor-lingand Interactions -- Rutgers, NJ" Sept. 26-28, 1990

Folder 42

"Stanford Human Genome Project -- Boon or Bane? --CA" Jan. 11-13, 1991

Folder 43

"2nd International IGF Symposium -- San Francisco" Jan. 12-16, 1991

Folder 44

"Isidore S. Edelman Symposium -- Columbia U. -- NY" April 18, 1991

Folder 45

"Chemistry & Genetics -- Workshop on Structure and Function of Mutated Proteins -- Florence" Aug. 26-30, 1991

Physical Description: PHOTOS
Folder 46

"3rd Pacific Rim Biotech Conference -- Taipei [1988-1992]" Aug. 19-21, 1992

Folder 47

"Table Ronde Roussel" N.d.

Physical Description: PHOTOS
Carton Carton 10

SUBGROUP 4 -- BUSINESS COMMITMENTS

Carton Ctn. 10, Folder 48

"Biomedical Research, Inc. (BMR) -- Chang & Susor" 1979

Folder 49

"Hana Biologics" 1981-1986

Folder 50

"Harbor Bay Isle" May-September 1981

Folder 51

"Harbor Bay Isle -- California Biotechnical Institute" July-Aug. 1981, n.d.

Folder 52

"Harbor Bay Isle" July-Nov. 1981

Folder 53

"Harbor Bay Isle -- Biotechnology Research Park" 1980, Aug.-Nov. 1981

Folder 54

"Harbor Bay Isle" 1981-1983

Folder 55

"Harbor Bay Isle -- California Biotechnical Institute" n.d.

Folder 56

"Meridian Instruments" 1982-1985, n.d.

Folder 57

"Meridian Instruments" 1985-1987

Folder 58

"Miscellaneous Commercial 1980-1983

Carton Cartons 11-13

SUBGROUP 5 -- PATENT FILES [RESTRICTED]

Carton Ctn. 11, Folder 1

European Patent Applications - 1961-1980

Folder 2

UC6-UC6c: Hepatitis - "Non Passageable Viruses" 1979-1984

Folder 3

UC6-UC6c: Hepatitis - "Non Passageable Viruses" 1978-1984

Folder 4

UC6-UC6c: Hepatitis - "Non Passageable Viruses" 1979-1985

Folder 5

UC6-UC6c: Hepatitis - "Non Passageable Viruses" 1979-1993

Folder 6

UC6a: Hepatitis - "Non Passageable Viruses" --Notes 1981, n.d.

Folder 7

UC6ab: Hepatitis - "Non Passageable Viruses" 1980-1990

Folder 8

UC12: "Expression of Hormone Genomic Clones" (abandoned) 1980-1984, n.d.

Folder 9

UC16: "DNA Expression Vector Suitable for Direct Expression of a Foreign Gene" (approved) 1980-1992

Folder 10

UC17: "Novel Somatostatins" (discontinued) 1980-1987, n.d.

Folder 11

UC19: "Amplified Expression Vector" (approved) 1980-1983

Folder 12

UC22: "Vaccine Capable of Eliciting Multivalent Antibodies" 1980-1987

Folder 13

UC24: "Production of High Levels of Hepatitis B Antigens in Mammalian Cells" 1980-1987, n.d.

Folder 14

UC25: "Yeast Expression Vectors and the Isolation of Yeast High Expression Promoters" (active) 1981-1982, n.d.

Folder 15

UC26: "Synthesis of Human Virus Antigen by Yeast" (approved) 1977-1983

Folder 16

UC26: "Synthesis of Human Virus Antigen by Yeast" 1981-1985

Folder 17

UC26: "Synthesis of Human Virus Antigen by Yeast" 1981-1988

Folder 18

UC118-80: "Amylase Preparation by Cloning" (rejected) 1980-1985, n.d.

Carton Ctn. 12, Folder 1

UC Case # 84-108-1: "Differntiative Expression Modules" 1984-1987

Folder 2

UC Case # 84-108-1: "Differntiative Expression Modules" 1988-1993

Folder 3

UC Case # 84-108-1: "Differntiative Expression Modules" 1993-1994

Folder 4

UC Case # 84-108-1: "Differntiative Expression Modules" 1984

Folder 5

UC Case # 84-108-1: "Differntiative Expression Modules" 1984

Folder 6

UC Case # 85-068-01: "Molecular Cloning of Human Placental Alkaline Phosphatase" (discontinued) 1985

Folder 7

UC Case # 87-035-3: "General Method for Producing and Selecting Peptides w/ Specific Properties" (approved) 1987-1993

Folder 8

UC Case #87-246: "Recombinant Nerve Growth Factor" (rejected) 1987-1993

Folder 9

Interference # 100,596: "Gilbert, et al., v. Rutter, et al." 1977-1983

Folder 10

Interference # 100,596: "Gilbert, et al., v. Rutter, et al." 1979-1991

Folder 11

Interference # 100,596: "Gilbert, et al., v. Rutter, et al." -- Lab Notes n.d.

Folder 12

Interference # 100,596: "Gilbert, et al., v. Rutter, et al." -- Lab Notes n.d.

Folder 13

Interference # 100,596: "Gilbert, et al., v. Rutter, et al." -- Lab Notes n.d.

Folder 14

Gilbert/Murray 1978-1991

Physical Description: FAX
Folder 15

Genentech -- European Patent Applications -- Insulin and Somatostatin 1977-1979

Folder 16

Genentech Dispute 1978-1982

Folder 17

Genentech Dispute 1976-1982, n.d.

Box Box 13, Folder 1

Eli Lilly Correspondence 1977-1979

Folder 2

Eli Lilly -- Contracts and Agreements 1978-1979

Folder 3

Eli Lilly - Genentech Settlement 1978, 1980

Folder 4

UC v. Genentech, Genentech v. Eli Lilly -- Legal Papers 1978-1991, n.d.

Folder 5

UC v. Genentech, Genentech v. Eli Lilly -- Defendants Exhibits #64-75 1991