Scope and Content of Collection
Title: Harry F. Noller papers
Collection number: UA 43
Noller, Harry F.
25 half cartons and 6 boxes
University of California, Santa Cruz. University Library.
Santa Cruz, California 95064
Abstract: Contains manuscript versions and offprints of articles, notebooks, and miscellany concerning RNA research.
Physical location: Stored offsite at NRLF: Advance notice is required for access to the papers.
Languages represented in the collection:
Collection open for research.
Property rights reside with the University of California. Literary rights are retained by the creators of the records and
their heirs. For permission to publish or to reproduce the material, please contact the Head of Special Collections and Archives.
Harry F. Noller papers. UA 43. University Archives, University Library, University of
California, Santa Cruz.
Transferred to University Archives by Harry F. Noller.
Harry F. Noller's work has led to fundamental changes in our thinking about the role of RNA in the many steps of protein synthesis.
He has used the full range of techniques including traditional biochemical as well as high resolution structural analysis
to elucidate mechanisms of protein synthesis. His contributions to the sequencing and of genes encoding ribosomal RNAs and
to phylogenetic and other analysis of these data led to insights into the secondary structure of these molecules and to functional
inferences. Chemical probing and crosslinking experiments provided the key insights to appreciate the possibility that the
peptidyl transferase activity of the large subunit of the ribosome may comprise RNA. His subsequent refined structural analysis
building on results from biochemical analysis of stripping of proteins from the large ribosomal subunit and assaying for peptidyl
transferase activity has provided a significant contribution to the full understanding of RNA catalysis of peptide bond synthesis
and other aspects of ribosome structure and function and protein synthesis.
A native of Oakland, California, Harry Noller received Ph.D. in Chemistry from the University of Oregon (1965). Following
postdoctoral work at the Medical Research Council Laboratory of Molecular Biology, Cambridge and the Institute of Molecular
Biology, University of Geneva, he joined the Department of Biology, University of California, Santa Cruz as Assistant Professor
(1968), becoming Professor in 1979. He has been Robert L. Sinsheimer Professor of Molecular Biology since 1987 and since 1992,
Director, Center for Molecular Biology of. He was Sherman Fairchild Distinguished Scholar, Division of Biology, California
Institute of Technology (1989-1990).
He is a member of the American Academy of Microbiology, the American Academy of Arts and Sciences, The RNA Society, The National
Academy of Sciences, and The American Association for the Advancement of Science and others. He presented the Harvey Lecture
at Rockefeller University (1989), and has received the Rosensteil Award in Basic Biomedical Science (2001), AAAS Newcomb Cleveland
Prize (2002), Speaker of the Year, Netherlands Society for Biochemistry and Molecular Biology (2002), RNA Society Lifetime
Achievement Award (2003), Massry Prize (2004), and the Paul Ehrlich and Ludwig Darmstaedter Prize (2007). He has authored
or co-authored approximately 200 high impact publications and has trained many outstanding students and postdoctoral fellows.
Text from The Gairdner Foundation website.
Scope and Content of Collection
The collection consists mainly of manuscript versions and offprints of articles on, for example, RNA structural analysis,
sequencing, peptidyl transferase, aspects of ribosome structure and function and protein synthesis.
Arranged following donor order.
The following terms have been used to index the description of this collection in
the library's online public access catalog.
Noller, Harry F.--Archives.
University of California, Santa Cruz--Faculty--Archives.
University of California, Santa Cruz. Dept. of Molecular Cell and Developmental Biology.
Genres and Forms of Material
Index Terms Related to this Collection
Online Archive of California.